MANAGEMENT OF GESTATIONAL DIABETES AND HYPERTENSIVE DISORDERS OF PREGNANCY

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MANAGEMENT OF GESTATIONAL DIABETES AND HYPERTENSIVE DISORDERS OF PREGNANCY

CHAPTER ONE

INTRODUCTION

Background of the study

Increased understanding of the epidemiologic context, pathophysiology, and treatment efficacy of gestational diabetes mellitus (GDM) has raised corollary questions regarding subsequent morbidities, in addition to diabetes, sustained by patients with this diagnosis. Both hypertension and vascular disease have been examined as conditions that may be predicted by GDM. Obesity and insulin resistance are central attributes of both GDM and the metabolic syndrome. These characteristics and dyslipidemia are associated with endothelial dysfunction, oxidative stress, and overexpression of inflammatory responses, all of which contribute to vascular disease. These associations have significant public health ramifications because of the current epidemic of obesity, affecting individuals of all age-groups. The recent report of Crowther et al. (1) confirming the efficacy of screening for and treatment of mild-to-moderate levels of glucose intolerance in mid-pregnancy in reducing both perinatal and maternal morbidity has set the stage for universal maternal screening and thereby identifies a cohort of young women (as many as 200,000 annually in the U.S.) who may be at risk for subsequent hypertension and vascular disease. Recent trials of exercise and dietary interventions and pharmacological treatments suggest that such interventions may reduce late post-gestational morbidity among women with prior GDM. Consequently, questions about the association of GDM and subsequent hypertension and vascular disease are timely and important.

Statement of the problem

There may have been previous researches in this subject. This work gives further explanations and analysis in management of gestational diabetes and hypertensive disorders of pregnancy

Objectives of the study
To understand the impact of gestational diabetes and hypertensive disorders on health status pregnant women
To understand the relationship between gestational diabetes and hypertensive disorders and health development among pregnant women

Research questions
What is the impact of gestational diabetes and hypertensive disorders on health status pregnant women
What is the relationship between gestational diabetes and hypertensive disorders and health development among pregnant women
1. Research hypothesis

H0: There is no relationship between gestational diabetes and hypertensive disorders and health development among pregnant women

H1: There is a relationship between gestational diabetes and hypertensive disorders and health development among pregnant women

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